## Malaria RDT product testing: interactive guideThis interactive guide is designed to help select malaria RDTs with the specific performance characteristics required by national malaria control programmes, based on the results of the WHO-FIND malaria RDT product testing programme Round 1 (2008), Round 2 (2009), Round 3 (2010), Round 4 (2012) and Round 5 (2013). |

Choose the parameters to display by clicking on the buttons below:

Panel detection score, 200 parasites/μl
Panel detection score, 2000-5000 parasites/μl
False positive ratesInvalid rate
Heat stability, 200 parasites/μl
Heat stability, 2000 parasites/μl
Test lines: order and target antigens
Blood volume
Buffer volume
Reading time

Table View | Chart View (select products to compare by clicking, only compatible with ~10 products) |

Product | Manufacturer | Catalogue No | Panel detection score (%) | False positive rates (%) | Invalid rate (%)^{l} |
Positive tests results (%) for P. falciparum (Pf line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive tests results (%) for P. falciparum (Pan line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive tests results (%) for P. falciparum (Pf line) at 2000 parasites/μl. Lots 1 and 2 combined |
Positive tests results (%) for P. falciparum (Pan line) at 2000 parasites/μl. Lots 1 and 2 combined |
Test lines | Blood volume (μl) | Buffer volume (nrs of drops) | Reading time (minutes) | ID | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

200 parasites/μl, P. falciparum samples^{a, c} |
200 parasites/μl, P. vivax samples^{a, d} |
2000 or 5000 parasites/μl, P. falciparum samples^{a, c} |
2000 or 5000 parasites/μl, P. vivax samples^{a, d} |
200 parasites/μl, P. falciparum samples (false positive non Pf infection)^{e} |
2000 or 5000 parasites/μl, P. falciparum samples (false positive non Pf infection)^{g} |
200 parasites/μl, P. vivax samples (false positive Pf infection)^{f} |
2000 or 5000 parasites/μl, P. vivax samples (false positive Pf infection)^{h} |
Total. Clean negative samples. False positive Plasmodium spp. infection^{b,i} |
Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | 1st (closest to control line) | 2nd | 3rd (Furthest from control line) | Min. | Max. |

**Notes:**

^{a} A sample is considered detected only if all RDTs from both lots read by the first technician, at minimum specified reading time, are positive

^{b} The total number of times a positive result for malaria was generated when it should not have been

^{c} Round 1, n=79; Round 2, n=100; Round 3, n=99; Round 4, n=98; Round 5, n=100

^{d} Round 1, n=20; Round 2, n=40; Round 3, n=35; Round 4, n=34; Round 5, n=35

^{e} For combination tests, Pan or Pv line, only, positive indicates a false positive non P. falciparum infection (Round 1 n=316; Round 2, n=400; Round 3, n=396; Round 4, n=392; Round 5, n=400)

^{f} Pf line positive indicates a false positive P. falciparum infection (Round 1, n=80; Round 2, n=160; Round 3, n=140; Round 4, n=136; Round 5, n=140)

^{g} For combination tests, Pan or Pv line, only, positive indicates a false positive non-P. falciparum infection (Round 1, n=158, Round 2, n=200; Round 3, n=198; Round 4, n=196; Round 5, n=200)

^{h} Pf line positive indicates a false positive P. falciparum infection (Round 1, n=40; Round 2, n=80, Round 3, n=70; Round 4, n=68; Round 5, n=70)

^{i} Round 1, n=168; Round 2, n=200; Round 3, n=200; Round 4, n=232; Round 5, n=236

^{j} Product resubmission, results from most recent round of testing replace previous results.

^{k} PDS presented in the table is based on a positive pf test line (either pf-HRP2 or pf-pLDH). For test line specific results refer to the tables and annexes in the full reports.

^{l} Round 1, n=954; Round 2, n=1240; Round 3, n=1204; Round 4, n=1192; Round 5, n=1214

Complete results of the WHO-FIND malaria RDT product testing programme (2013)